We all know that, if the President dies, the Vice President becomes President. What is less known, and less frequent, is what happens if the Vice President vacates the office for some reason. This occurrence has happened on eighteen different occasions - yet, only twice in American history has a Vice President been appointed by the U.S. Senate. So, off of Pocket Trivia: US History - Who was the first Vice President appointed by the United States Senate? Was it Charles Fairbanks, Nelson Rockefeller, Hubert Humphrey or Gerald Ford?