I cannot think of a preamble to this quote, one of the best of any 80s movie, so let's just go for it today. From Pocket Trivia: 80s Trivia, what movie features this gem: "Why don't you make like a tree, and get out of here?" Is it Cocoon, Back to The Future, The Goonies or Spies Like Us?
Come on now. This classic comes from Back to The Future and is spoken by one of the best cross-generational villans of all time, Biff Tanner.
The quote is actually used in two Back to The Future movies - Back to the Future 1 and Back to the Future 2. Personally, I think that its use in the 2nd movie is even funnier - in that movie, young Biff says the butcher quote to older Biff, who proceeds to smack Biff and yell at him for butchering the quote. "It's LEAVE! Make like a tree and LEAVE, you idiot!"